Cryo-electron microscopy (cryo-EM) can help scientists determine the three-dimensional structure of proteins in unprecedented detail. Jacques Dubochet, former group leader at EMBL, shared the 2017 ...

The Cryo-Electron Microscopy Center supports industry, academic, government, and non-profit research institutes, providing single-particle and microcrystal electron diffraction capabilities. We offer ...

Cryo-EM performance is fundamentally constrained not only by technical preparation challenges but also by intrinsic protein disorder, where dynamic and flexible regions remain unresolved despite ...